Join to apply for the Research Assistant role at Murdoch Children's Research Institute (MCRI).Role Type: 2-year full time contractSalary: $84,000 - $94,014 per annum plus superannuationThe Opportunity: We are seeking a highly motivated and experienced Research Assistant to join the Stafford Fox Drug Discovery Facility within the MCRI Stem Cell Medicine Theme. This is an exciting role that involves contributing to high content and high throughput drug screening activities using cutting-edge technologies.In This Position, You Will:Contribute to assay development, phenotypic drug screening, and hit validation using human stem cell-derived cells and organoids.Operationalise new and existing workflows for automated liquid handling robots and confocal imaging.Work closely with senior team members during automation development and drug screening activities.Prepare laboratory SOPs, culture cell lines, and maintain cell stocks.Handle ordering reagents, keeping electronic inventories and records up to date, and preparing reports.You’ll be an essential part of the team supporting biomedical research activities and helping to accelerate our understanding of disease mechanisms and potential therapies.About Your New Team:Our Stem Cell Medicine Theme is dedicated to using advanced stem cell technologies to drive discoveries in stem cell biology and apply these insights to medical outcomes. We are focused on understanding the causes of childhood diseases, screening for new treatments, and advancing regenerative medicine. Our team’s expertise spans stem cells, gene editing, transcriptomics, phosphoproteomics, and bioengineering to model complex diseases and develop stem cell-based therapies.This position also offers the exciting opportunity to participate in The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), an international research consortium with members from University of Copenhagen (Denmark), Leiden University Medical Centre (The Netherlands), and Murdoch Children’s Research Institute (Australia).Your Responsibilities Include:Contribute to pre-clinical cell-based drug discovery research projects.Assist in the development and validation of assays for cell-based phenotypic screening and their transfer to robotic systems for high throughput screening.Assist in the development and testing of automation procedures (liquid handling, drug dispensing and imaging).Assist on executing high throughput primary and secondary screening drug screens and generation of high-quality screening data.Assist in the training of internal and external users on equipment usage, data visualisation and basic analysis.Develop and effectively apply a broad spectrum of practical laboratory skills; including molecular biology, cell culture, biochemistry, assay development, and the use of automated equipment.What We Need From You:Degree/Honours/Masters qualification in Science or related discipline.Demonstrated capacity to work independently and collaboratively in a team environment.Excellent time management, organisational and analytical problem-solving skills.Experience with automation, including liquid handling, image acquisition and image analysis.Strong interpersonal and communication skills.Demonstrated experience using image analysis software (e.g., Cell Profiler, Fiji, ImageJ).For full viewing of responsibilities and requirements please refer to the position description.Any specific questions related to this position should be directed to Dr Alejandro Hidalgo-Gonzalez at Alejandro.hidalgogon@mcri.edu.au.What’s in it for you?Salary packaging, including entertainment and novated leases.Be part of a leading research institute focused on cutting-edge stem cell research and drug discovery.Collaborate with experts in stem cells, gene editing, and regenerative medicine.Gain international exposure through participation in the reNEW consortium.Contribute to innovative research with a focus on childhood diseases and medical outcomes.Who We Are:Murdoch Children’s Research Institute envisions a transformative future for child health. Our institute is a hub of impactful scientific breakthroughs, particularly in early interventions, enhanced diagnosis, prevention, and potential cures. We thrive on collaborative, multidisciplinary problem-solving to address challenging queries in child health. Committed to inclusivity and respect, we foster a positive working environment that values diverse backgrounds and experiences.We are committed to the safety of children and young people and take a zero-tolerance approach to all forms of child abuse, exploitation and harm. Child safety is prioritised in our decision-making at all levels of the Institute.Join Us!If you believe this role is a good fit for you, please apply by submitting:Your resume.A cover letter addressing the selection criteria.Ensure these documents are combined into a single PDF file. We welcome individuals of diverse genders, ages, ethnicities, cultural backgrounds, abilities, religions, and sexual orientations in our workplace. We actively encourage talented individuals from all walks of life to apply for our job openings.Please note, we reserve the right to close the vacancy prior to the closing date once a sufficient number of applications have been received. No recruitment agencies please.Applications close: 11 April 2025 AUS Eastern Daylight time.
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